Former NFL wide receiver Vincent Jackson was found dead Monday in a Florida hotel room, according to The Hillsborough County (Florida) Sheriff's Office.

The body of the 38-year-old Jackson was found at approximately 11:30 a.m. ET on Monday at the Homewood Suites in Brandon, Florida. Police said there were no apparent signs of trauma, and the Hillsborough County Medical Examiner's Office will determine the cause of death.

The Hillsborough County Sheriff's Office said it has opened an investigation.

According to hotel staff, Jackson, who is a South Tampa resident, checked into the hotel on Jan. 11 and had been staying in a room since that date.

Jackson's family reported him missing on Wednesday and a formal report was filed Thursday, but police located Jackson at the Homewood Suites on Friday. The missing persons case was canceled after Jackson's well-being was confirmed.

"My heart aches for the many loved ones Vincent Jackson leaves behind, from his wife and children to the Buccaneers nation that adored him," Sheriff Chad Chronister said in a statement. "Mr. Jackson was a devoted man who put his family and community above everything else.

"He will be sorely missed by not only football fans across the country, but also the people here in Hillsborough County who reaped the benefits of his generous contributions."

The son of military parents, Jackson founded the Jackson In Action 83 Foundation, a nonprofit to support military families. The foundation tweeted Monday that Jackson's "wife and family ask that everyone respect their privacy at this time."

Jackson last played in the NFL in 2016 with the Tampa Bay Buccaneers, the team with which he spent the final five seasons of his career. He is ranked fourth in franchise history with 4,326 receiving yards and 10th with 268 receptions.

Buccaneers owner and co-chairman Bryan Glazer said in a statement that Jackson was a "consummate professional" and even with his accomplishments on the field, "his greatest achievements as a Buccaneer were the four consecutive nominations he earned as our Walter Payton Man of the Year."

Rest in peace, Vincent Jackson. 🙏 pic.twitter.com/ik3GYZjQDr

— Tampa Bay Buccaneers () February 15, 2021

He played his first seven seasons with the Chargers, who selected him in the second round (61st overall) of the 2005 draft. He is tied for eighth in franchise history for touchdown receptions (37) and is 10th in receiving yards (4,754).

The Chargers said in a statement that Jackson was a "fan favorite not only for his Pro Bowl play on the field but for the impact he made on the community off of it."

gone too soon 💙 pic.twitter.com/lQEtPjNQ4w

— Los Angeles Chargers () February 15, 2021

Buccaneers wide receiver Mike Evans was among several of Jackson's former teammates to react to the news on Twitter, writing: "V Jax thank you for everything I love you big bro. Praying for your family Rest in Paradise."

V Jax thank you for everything I love you big bro. Praying for your family Rest in Paradise

— Mike Evans () February 15, 2021

Overall, Jackson had 540 catches for 9,080 yards and 57 touchdowns and was selected to three Pro Bowls in his 12-season career.